Serious RTC this morning collision involved a silver Ford Focus and a black Suzuki SX4.
Its believed it happened around 2.15 am
One of the main routes into Grimsby town centre is closed this morning following a serious crash overnight.
Cromwell Road and Dudley Street are closed up to Deansgate Bridge.
Cromwell Road is closed in both directions closed between Bargate and Marshall Avenue.
Littlefield Lane is also reported to be closed between Chantry Lane and Rosalind Avenue in both directions.
Large amount of police are at the scene.
More updates to follow.